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First nourishing meal in two
months...
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Still Defending...
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Congratulations,
Wendy and Amy!!!
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HAPPY
BIRTHDAY!! Bob and John
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View
the Pix from the **Mechanisms
of Aging and Dementia Training Grant Day***
Friday, February 11, 2005
Peninsula Hotel, 108 E Superior (at N Michigan Ave), Chicago
Click Here
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Honoraria:
2005 Inaugural Lecturer, "Understanding
and Enhancing Learning Abilities in the Aging Brain,"
Manoa Colloquium, University of Hawaii, Honolulu, Hawaii,
February 22, 2005
Rotating
Students in Dr. Disterhoft's lab this
academic year include:
Fall:
Mariana Jimenez and Aaron Schain
Winter: Luke Flores, Yoonsoo Kim and Bridget McKay
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Visiting Researchers:
Jim Kehoe returned from Australia for a brief visit,
and presented a departmental seminar entitled "Extinction:Context
Can Make All the Difference and None at All" on July
6, 2004.
New Funding:
A Society for
Neuroscience Minority Neuroscience Fellowship Program (SFN-MNFP):
for Robert Galvez. The funding will extend from 4/1/05
through 3/31/07,in support of Robert's research to characterize
learning induced cortical plasticity as a function of age. Specifically,
he has been working on establishing and subsequently characterizing
cortical changes in response to eyeblink conditioning with vibrissae
stimulation as the conditioned stimulus in rabbits.
From the National Institutes of Health:
John Desmond, PI, John Disterhoft, Co-Investigator
6/01/04-5/31/09
fMRI Analysis of Aging and Awareness in Conditioning
A new
application to apply fMRI studies of the BOLD response in human
brain during acquisition of eyeblink conditioning. The brain systems
underlying learning and awareness will be visualized in young
and aging subjects using the 3 Tesla magnet at the Lucas Imaging
Center of Stanford University. NIA#
Geinisman, PI; Disterhoft,
Co-Investigator. 9/1/99 - 8/31/09
Synaptic Substrates of Age-Dependent Memory Deficits
The goals of this project are to investigate the synaptic mechanisms
of age-related deficits in learning with a combination of unbiased
quantitative electron microscopic, behavioral and electrophysiological
techniques applied to the CA1 and dentate regions of the hippocampus.
NIA#R01 AG021501, John Desmond, PI, John Disterhoft, Co-Investigator
6/01/04-5/31/09
fMRI Analysis of Aging and Awareness in Conditioning.NIA# 1 R01
AG17139
For Dr. Disterhoft's competetive renewal application "Forebrain
Cerebellar Interactions During Learning". This is a single
neuron recording and reversible lesion study investigating the
function of sites on the pathway by which forebrain and cerebellum
interact during hippocampally dependent trace eyeblink conditioning
and during consolidation of the learning response.
For "Neurophysiological Bases of functional MRI signals".
This was a new application designed to examine the generation
of the BOLD response in functional magnetic resonanace imaging
with a combination of imaging and neurophysiological techniques
in the conscious, restrained rabbit.
For Dr. Masuo Ohno's new funding CaMKII and Neuronal
Excitability Changes in Learning
For the competetive renewal of Dr. Disterhoft's Merit Award
from the NIA for his project Slow Outward Currents and Learning
in Aging Hippocampus
New Lab Members:
Dr. CJ Han joined the lab in Mid-November of 2003. She received
her Ph.D. in Psychology from SUNY Stonybrook, and most recently
completed postdoctoral studies at CalTech under Cristof Koch and
David Anderson.
Roberto Galvez
joined the lab on April 1, 2004. He recently completed his Ph.D.
with Dr. William Greenough at the University of Illinois in Urbana/Champaign
and is taking a postdoctoral position in Dr. Disterhoft's Mechanisms
of Aging and Dementia Training Program.
On a More Personal Note:
Dr. Aldis Weible and Rie Yoshida were recently married
in a traditional Japanese ceremony in Rie's home city of Osaka,
Japan.
CLICK
HERE to view a nationally broadcast synopsis of recent findings
aired by ScienCentral in January 2004. The research was done by
Dr. Masuo Ohno. Funding for
the relevant research grant, entitled "Interactions of APP
and BACE on Behavior and Hippocampal Physiology in Aging Mice"
was initiated and continues to be funded by the Alzheimer's Association
and was published in Neuron,
2004, 41, 27-33.